For the Peptide-Curious
and Biohackers

A small-molecule enzyme blocker (not actually a peptide) marketed alongside peptides as a fat-loss compound; it reduces obesity in mice by inhibiting the enzyme NNMT and raising cellular NAD+, but there is no published human efficacy or safety data at all — so for people, it is a purely preclinical compound being sold as if it were proven.

A small modified fragment of human growth hormone, designed to trigger fat-burning without growth hormone's other effects; it was developed as an obesity drug, showed an early positive signal, but its larger pivotal trial failed to establish meaningful weight loss and development was discontinued — leaving today's 'fat-loss peptide' marketing well ahead of the human evidence.

A synthetic 15-amino-acid peptide, derived from a protein in human gastric juice, that is widely promoted for injury and gut healing but whose evidence is almost entirely from animal studies.

A synthetic growth-hormone-releasing-hormone (GHRH) analog, sold gray-market and usually stacked with ipamorelin; it reliably and durably raises growth hormone and IGF-1 in one human study, but its clinical development was abandoned after a participant death and it has no human evidence for the muscle or anti-aging uses it's sold for.

A synthetic four-amino-acid Russian peptide promoted for longevity and telomere lengthening; it does activate telomerase in cultured human cells and extends lifespan in animals, but the human longevity claims lean on small, non-randomized Russian data — much of it from a related pineal extract, not this peptide — so the 'live longer / reset your telomeres' marketing far outruns the proof.

A naturally occurring copper-binding tripeptide with decades of skin-science research — as a topical cream it has real human data for wrinkle reduction, but the injectable form biohackers use has no controlled human evidence and can't be legally compounded.